Rabbit enterotoxaemia: Purification and preliminary characterisation of a toxin produced by Clostridium spiroforme

Identification of the cellular receptor of Clostridium spiroforme toxin.

Clostridium spiroforme produces the binary actin-ADP-ribosylating toxin CST (C. spiroforme toxin), which has been proposed to be responsible for diarrhea, enterocolitis, and eventually death, especially in rabbits. Here we report on the recombinant production of the enzyme component (CSTa) and the binding component (CSTb) of C. spiroforme toxin in Bacillus megaterium. By using the recombinant t...

Some properties of Beta Toxin produced by Clostridium haemolyticum strain IRP 13

Alpha Toxin Purification and Antibody Production Against Local Strain of Clostridium septicum NH2

BACKGROUND: Clostridium septicum has played a significant role as a causative agent of many acute fetal diseases in man and animals. Alpha- toxin is the main factor in the pathogenesis of C. septicum with hemolytic, necrotic and lethal activities. OBJECTIVES: The study was designed to evaluate alpha-toxin purification and antibody production rate against a local strain of C. septicum NH2 which ...

ISOLATION AND CHARACTERISATION OF Clostridium histolyticum AND IT’S TOXIN

Article History Received on:30-01-2015 Revised on:15-02-2014 Accepted on:24-02-2014 ABSTRACT A gram positive, motile, strictly anaerobic bacterium was isolated from the sediment samples of Vellar estuary, India and was identified as Clostridium sp. by biochemical methods. The organism was found to be resistant only to erythromycin among the various antibiotics tested. The culture supernatant wa...

A role for the Clostridium perfringens beta2 toxin in bovine enterotoxaemia?

Non-enterotoxigenic type A Clostridium perfringens are associated with bovine enterotoxaemia, but the alpha toxin is not regarded as responsible for the production of typical lesions of necrotic and haemorrhagic enteritis. The purpose of this study was to investigate the putative role of the more recently described beta2 toxin. Seven hundred and fourteen non-enterotoxigenic type A C. perfringen...